Prostate cancer spheroids are an important in vitro model for studying the biological behavior of tumors, including tumor heterogeneity, drug response, and the effects of the tumor microenvironment. Alfa Cytology offers a one-stop prostate cancer spheroids development service, ensuring that your research projects can move forward with efficiency and precision.
Prostate cancer spheroids are three-dimensional (3D) cell culture models that mimic the mechanical tension in tumor tissues and provide a more representative pathophysiological model than traditional 2D cultures. These cell spheroids are formed in vitro by culturing prostate cancer cell lines such as LNCaP, PC3, and VCaP. They are able to replicate the 3D structure of tumors and cell-cell interactions, which is crucial for studying the role of tumor heterogeneity in cancer development, prognosis, and treatment.
Fig. 1 LNCaP spheroid
morphology and doubling time. (Bastian, J. L. D., et al. 2024)
The main differences between spheroids and organoids in prostate cancer are as follows.
Alfa Cytology is dedicated to offering a full spectrum of spheroid development services for prostate cancer studies, encompassing the creation and refinement of tailored 3D spheroid models. Our expert team is devoted to fulfilling your precise requirements for spherical cell cultures in the realms of tumor aggression analysis, drug resistance profiling, and tumor microenvironment investigations.
Cell Collection
Cell Culture
Spheroid Formation
Functional Analysis
![]() |
![]() |
|
Type | Primary Cell Spherical Model | Prostate Cancer Spherical Model |
Source | Primary cell spheroids are directly sourced from prostate cancer tumor tissue, forming 3D structures through in vitro cultivation of fresh primary cells. | Prostate cancer spheroids are developed from cell lines or patient cells, aggregating into spheres under specific conditions like low-attachment plates or suspension culture. |
Application | Primary cell spheroids replicate tumor microenvironments and interactions, maintaining diversity and heterogeneity, and are used for studying early tumor stages, drug responses, and personalized therapies. | Primary cell spheroids replicate tumor microenvironments and interactions, maintaining diversity and heterogeneity, and are used for studying early tumor stages, drug responses, and personalized therapies. |
With extensive experience and advanced platforms, we offers a one-stop prostate cancer spheroids development service. We guarantee that your research endeavors are equipped with superior, dependable prostate cancer spheroid models. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.
Reference