Single-Cell Omics Services for Cancer Research
Single-cell omics has emerged as a transformative technology in cancer research, enabling a comprehensive analysis of the heterogeneity and complexity of tumors. Alfa Cytology, a leading preclinical CRO, offers a wide range of single-cell omics services.
Introduction to Single-Cell Omics
Single-cell omics refers to a suite of techniques that enable the comprehensive profiling of individual cells at various molecular levels, including genomics, transcriptomics, epigenomics, proteomics, and metabolomics. These techniques have revolutionized cancer research by uncovering previously inaccessible information about cellular heterogeneity, clonal evolution, and tumor microenvironments.
Fig.1 scMulti-omics profiling and application examples in immuno-oncology. (Ma, A., et al., 2022)
The field of single-cell omics has grown exponentially, fueled by advancements in sequencing technologies and computational biology. Current research is focused on deciphering the complex ecosystem of tumor cells, immune cells, and the tumor microenvironment to understand their interactions and influence on tumor behavior.
Our Services
At Alfa Cytology, we provide a comprehensive analysis of the cellular heterogeneity and complexity within tumors, enabling breakthrough discoveries in cancer biology. With our advanced technologies and expertise, we empower researchers to unlock the full potential of single-cell analysis and accelerate the development of innovative cancer therapies. Our services include, but are not limited to:
| Service Options |
Description |
| Single-Cell Genomics Services |
Comprehensive analysis of the genomic landscape of individual cancer cells, providing insights into genetic alterations, clonal evolution, and tumor heterogeneity. |
| Single-Cell Transcriptomics Services |
Profiling gene expression at the single-cell level, allowing for the identification of cell types, characterization of cellular states, and exploration of gene regulatory networks. |
| Single-Cell Proteomics Services |
Quantification of protein expression in individual cells, enabling the identification of protein markers, signaling pathways, and potential therapeutic targets. |
| Single-Cell Epigenomics Services |
Investigation of epigenetic modifications at the single-cell level, uncovering epigenetic heterogeneity and its impact on gene regulation and cellular phenotypes. |
| Single-Cell Immunomics Services |
Investigation of epigenetic modifications at the single-cell level, uncovering epigenetic heterogeneity and its impact on gene regulation and cellular phenotypes. |
Workflow of Our Services
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Sample Preparation
We work closely with our clients to optimize sample collection and preparation protocols, ensuring high-quality single-cell suspensions.
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Omics Profiling
We utilize sequencing and analytical technologies to generate high-resolution data on the genomic, transcriptomic, or proteomic of individual cells.
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Interpretation and Reporting
We provide detailed reports and visualizations to interpret complex datasets and translate them into meaningful insights.
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Single-Cell Isolation
We employ advanced technologies, such as microfluidics or fluorescence-activated cell sorting (FACS), to isolate individual cells for downstream analysis.
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Data Analysis
We perform comprehensive data analysis, including , differential expression analysis, pathway analysis, and integration with other omics data.
Our Advantages
Largest Toolbox
Strong Expertise
One-stop Solution
Short Turnaround
At Alfa Cytology, we are committed to driving innovation in cancer therapy development. Our single-cell omics services pave the way for groundbreaking discoveries and personalized therapeutic strategies. If you are interested in our service, please contact us for more details.
Reference
- Ma, A., et al.; (2022). The use of single-cell multi-omics in immuno-oncology. Nature Communications, 13(1), 2728.
For research use only.
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