Breast Cancer Modeling Services
Introduction of Breast Cancer Experimental Models
Breast cancer (BC) is a malignant tumor occurring in the epithelial tissue of the breast, and it is also the second leading killer of all malignant tumors. According to molecular types, BC is mainly divided into Luminal A type, Luminal B type, HER2 overexpression type, and triple-negative BC. The successfully constructed BC models can help to further clarify the etiology of BC and explore the pathogenesis and therapeutic targets of BC. BC models play a vital role in the study of the prevention, occurrence, diagnosis, and treatment of human BC. BC models can be divided into in vivo models and in vitro models, including BC cell models (2D cell lines and 3D spheres), BC organoid models, and BC experimental animal models.
Fig. 1. Complex culture systems available to study BC. A schematic of how live tissue samples can be processed, cultured, and utilized for subsequent characterization and analysis. (Callaway MK, et al., 2023)
Our Services
BC is a highly heterogeneous disease, and the biological characteristics of tumors in different individuals or even in the same body are different. Therefore, it is necessary to establish various types of BC tumor models to achieve precise and individualized treatment of BC. Alfa Cytology has many years of experience in building BC models, based on our advanced platform and experienced scientists, we can build customized, cost-effective, high-quality BC models, including BC animal models, BC organoids models, and BC cell models.
| Models | Applications |
| Breast cancer animal models | It can be applied to the mechanism of BC occurrence and development in vivo, as well as drug detection for the prevention and treatment of tumor occurrence and development. |
| 3D Tumor Model for Breast Cancer | The currently available 3D breast cancer models represent many aspects of tumor physiology much better than the previously used 2D cultures. |
| Breast cancer cell models | It can be applied to the screening of anti-breast cancer tumor drug compounds and the verification of breast cancer treatment. |
In addition, we offer full laboratory services.
- Experimental consulting and design
- Selecting an appropriate cell line/cancer model
- Host animal selection
- Experimental observation and recording
- Post-experiment analysis
Application Fields
- BC pathology
- BC drug screening
- BC treatment
- BC prevention
- BC chemotherapy effect evaluation
- BC biomarkers discovery
- BC tumor growth and metastasis
Advantages of Our Services
- Scientific program design
- Strict quality control management
- Professional research team
- Rich project experience
- High-quality project services
Alfa Cytology is a CRO company with advanced platforms, professional scientists, and rich experience in BC research services. We are committed to providing customers with high-quality, comprehensive, and authoritative BC model services. If you are interested in our BC model service, please contact us, and we will formulate a detailed service agreement according to your plan and requirements, and improve the efficiency of your BC scientific research.
Reference
- Callaway MK, Dos Santos CO. Gestational Breast Cancer - a Review of Outcomes, Pathophysiology, and Model Systems. J Mammary Gland Biol Neoplasia. 2023 Jul 14;28(1):16.