The process of drug discovery and development is costly and time-consuming. Alfa Cytology offers developmental services for novel therapies against leukemia that include traditional cytotoxic chemotherapy, targeted agents addressing genetic and epigenetic alterations, and optimized approaches of immunotherapy.
A combination of cytarabine and anthracycline drugs represents the standard regimen for the treatment of AML. Resistance hampers single-agent approaches in achieving long-term outcomes. Heterogeneous diseases encourage the development of new targeted therapies against a diversity of mechanisms in leukemia and, in combinations or scheduled as substitutes of ineffectual chemotherapy, improve therapeutic outcomes.
Fig. 1. Novel targeted therapies in development for acute myeloid leukemia (AML). (Totiger, T.M. et al., 2023)
Alfa Cytology offers various therapy development services for leukemia, including, but not limited to.
Different types of leukemia require different therapies. We offer a tailor-made solution to drama drug development, targeting a specific leukemia disease so that the whole process of drug discovery can be sped up, therefore shortening the time frame for your research and development
Since leukemia represents a highly heterogeneous cancer with a multitude of gene mutations, various treatment modalities are used in clinical practice, from chemotherapy to novel targeted therapy, stem cell transplantation, or combinations thereof. The development services comprise different classes of therapeutic agents aimed at realizing the blueprint for leukemia drug discovery through novel therapeutic strategies.
Target-based drug discovery is the most widely used paradigm in drug discovery. The company undertakes integrated services designed to provide its clients with the optimum lead identification that speeds up the drug discovery process. We provide guidance throughout the drug development process.
Because preclinical studies provide a foundation for drug development, identifying suitable targets and validating their mechanisms is a cornerstone of leukemia drug development. Our multispecialty experience allows for the complete acceleration of classical drug discovery, hit identification, and lead optimization-with development possible for all new drugs or repurposing existing drugs for novel targets.
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Partner with Alfa Cytology to accelerate your journey of drug development against leukemia. Our tailor-made solutions, scientific in-the-field expertise, and commitment to innovation support your search for efficacious therapies and patient outcome improvement. Contact us now to learn more about how our services can assist your research and development endeavors.
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