3D Tumor Model Development

A 3D model of ovarian cancer is a 3D structure created using real ovarian cancer cells, designed to accurately mimic the tumor microenvironment. At Alfa Cytology, we have extensive experience in developing 3D models of ovarian cancer.

Introduction to 3D Tumor Model of Ovarian cancer

3D tumor analysis in ovarian cancer uses techniques like organoids, 3D cell culture, and bioprinting to replicate the tumor's natural environment. These models, mimicking the tumor's spatial structure and microenvironment, allow researchers to extract cells from patient tissues or use 3D-printed scaffolds. This facilitates detailed observation of tumor growth, migration, invasion, and drug responses. Such analysis enhances tumor understanding, aids in discovering therapeutic targets, and promotes personalized treatments, improving efficacy and reducing side effects.

Fig.1 3D model of ovarian cancer. (WATTERS K M, et al., 2018)

Cultivation of 3D Tumor Models

• Suspension Culture: Cells are suspended in the medium without attaching to any surface.
• Matrix Gel Culture: Cells are embedded in a gel-like matrix (e.g., Matrigel) that provides support and growth factors.
• Scaffolding: Cell growth is supported using a three-dimensional scaffold (e.g., biomaterials or synthetic polymers).
• Microfluidics: Utilizing microfluidic chips to precisely control the cell growth environment.
• Sphere Culture: Cells naturally aggregate to form spheres in a petri dish.

Our Services

Alfa Cytology is leveraging 3D tumor analysis to uncover cellular behavior and drug response mechanisms in ovarian cancer. By employing advanced 3D models, our research team can more precisely replicate the tumor microenvironment. This enhanced simulation facilitates the development of more effective therapeutic strategies.

3D Cell Culture

Our research team utilize three-dimensional scaffolds and gel cultures to more closely mimic the tumor microenvironment in vivo.

• Tumor Spheroid Culture
• Scaffold-Based Culture
• Co-Culture Models

3D Bioprinting

We use bioprinting technology to accurately deposit cells and biomaterials layer by layer, constructing spatial tissue models that closely resemble actual tumors.

• Cell-Matrix Printing Model
• Multicellular Tumor Models
• Biocompatible Scaffolds

3D Tumor Models of Ovarian Cancer

• Hydrogel-Based 3D Model: We provide ovarian cancer cell cultures using hydrogels (e.g., matrigel) to study cell-substrate interactions.
• Microfluidic Chip Model: Microfluidics is used to create complex 3D ovarian cancer models that replicate tumor blood flow and nutrient delivery.
• Co-Culture Model: Our research team co-culture ovarian cancer cells with stromal or immune cells to create a more complex and representative tumor microenvironment.

Assays for Ovarian Cancer 3D Model

By replicating the complex tumor microenvironment using a 3D model, a realistic 3D space has been created for studying ovarian cancer signaling pathways. This approach allows for precise observation and analysis of the interactions between cancer cells and surrounding tissues.

Alfa Cytology is pioneering innovation in 3D tumor modeling for ovarian cancer, revolutionizing cancer research and treatment development with cutting-edge technology. Our state-of-the-art facilities and multidisciplinary teams are committed to advancing scientific discoveries and translating these findings into clinical solutions. Contact us to learn how our 3D tumor model development services for ovarian cancer can enhance your research efforts.

! For research use only.