Cancer Cell-based Assays

Cancer cell-based assays play a pivotal role in unraveling the complexities of tumor biology, offering a controlled and reproducible platform for studying the efficacy of potential cancer therapeutics. Alfa Cytology is committed to advancing cancer research through our cancer cell-based assays.

Introduction to Cancer Cell-based Assays

Developing effective cancer therapies requires a comprehensive understanding of the cellular components in the tumor microenvironment (TME). Cancer cell-based assays involve the utilization of cultured cancer cells to evaluate various aspects of tumor biology, including but not limited to cell viability, proliferation, migration, invasion, and response to therapeutic agents.

Fig.1 Impact of immune cells within the tumor microenvironment. (Anderson, N. M., & Simon, M. C., et al., 2020)

These assays enable researchers to investigate tumor-specific characteristics and behaviors in a controlled laboratory setting. Cancer cell-based assays offer higher throughput capabilities, allowing for the screening of a large number of compounds or therapeutic interventions in a relatively short period. These assays provide valuable insights into the molecular mechanisms underlying tumor development and response to therapies, aiding in the design of personalized therapeutic strategies.

Our Services

At Alfa Cytology, we offer a comprehensive range of cancer cell-based assays that focus on different aspects of the immune system's role in tumor killing and response to treatment. Our services include, but are not limited to:

Immune-mediated Tumor Killing Assays

T Cell Killing Assay
Antibody-Dependent Cell Cytotoxicity (ADCC) Assay
Spheroid Immune-Mediated Tumor Killing Assays

Tumor Cell Based Assays

Cell Culture and Characterization
Cell Viability and Proliferation Assays
Apoptosis and Cell Death Analysis

T Cell Based Assays

Cytokine Response Assays
T Cell Proliferation Assay
T Cell-Mediated Cytotoxicity Assay
Immune Checkpoint Assays

Natural Killer Cell Based Assays

Cytotoxicity and Target Cell Killing Assays
Phenotypic Characterization of NK Cells
Evaluation of Immunomodulatory Effects

Macrophage Based Assays

Macrophage Polarization Assays
Macrophage-Tumor Cell Interaction Assays
Macrophage Functional Assays

Dendritic Cell Based Assays

Dendritic Cell Isolation and Characterization
Antigen Presentation Assays
Cell Interactions and Co-culture Assays

Our Advantages

Professional and well-trained core technical team.

Professional and well-trained technical team

Advanced experimental equipment

Empowering success through cooperation.

Empowering success through cooperation

Strict quality control system.

Strict quality control system

Cancer cell-based assays have emerged as a powerful tool for understanding the complex cellular interactions within the tumor microenvironment and predicting the response to therapeutic interventions. Alfa Cytology offers comprehensive suite of services, allowing for a holistic understanding of the interplay between cancer cells and the immune system. If you are interested in our service, please contact us for more details.

Reference

Anderson, N. M., & Simon, M. C. (2020). The tumor microenvironment. Current Biology, 30(16), R921-R925.

For research use only.