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Drug Development for Prostate Cancer

Every step of therapeutic drug development, from initial drug screening to final product approval, ensures exhaustive experimental testing and rigorous regulatory evaluation. At Alfa Cytology, we are committed to every aspect of drug discovery, providing comprehensive and detailed drug development services for prostate cancer therapeutics.

Introduction to Drug Development for Prostate Cancer

Prostate cancer is one of the major killers of malignant tumors in men, and more than hundreds of thousands of people are diagnosed with prostate cancer every year. Prostate cancer can spread to nearby organs such as the bladder or enter bones or other organs through the bloodstream or lymphatic system.

Prostate cancer that has spread to other parts of the body may also respond to therapy and may be controlled, but is unlikely to be cured. Therefore, the development of effective drugs to treat prostate cancer has been an important area of research for the pharmaceutical industry.

Fig. 1 Treatment of PCA by stages.Fig. 1 Treatment of PCA by stages. (Malik, J. A., et al. 2022)

Drug Development for Prostate Cancer

Recent research advances have shown that the development of innovative drugs shows great potential in the field of prostate cancer therapy. This mainly includes targeting new molecular targets, epigenetic-based drug development, and drug studies targeting the androgen receptor (AR) and its variants.

These advances have opened up new opportunities for more effective prostate cancer therapies. Additionally, they have the potential to reduce the risk of side effects associated with existing therapies.

Name Target Phase Company Country
H001 AR IND-enabling Halda Therapeutics USA
Proxalutamide AR Phase I Kintor Pharmaceutical Limited China
X-Synergy AR Phase I Kanpu Biopharma China
TAS-3681 AR Phase I Taiho Pharmaceutical Japan
KZR-261 AR Phase I/II TRACON Pharmaceuticals USA
TRC253 AR Phase I/IIA TRACON Pharmaceuticals USA
Darolutamide AR Market Approval Bayer AG & Orion Corporation Germany & Finland

Our Services

Our company has long specialized in the field of prostate cancer drug development. As experts in the field of prostate cancer drug discovery, we can offer a comprehensive suite of services designed to provide our clients with the necessary tools and expertise to overcome the obstacles to prostate cancer drug development. At Alfa Cytology, we offer one-stop drug development services for prostate cancer, providing our clients with comprehensive solutions that can be tailored to their specific needs.

Workflow of Drug Development

Drug Discovery

Drug Discovery
  • Target Identification
  • Hit Identification
  • Lead Optimization

Efficacy Evaluation

Efficacy Evaluation
  • In Vitro Testing
  • In Vivo Models
  • Mechanism Research

DMPK/ADME

DMPK/ADME
  • In Vitro & In Vivo
  • Bioanalysis
  • Metabolite Identification

Safety Assessment

Safety Assessment
  • Toxicokinetics
  • Genotoxicity
  • Acute & Chronic Toxicity

Our Advantages

We are committed to providing efficient, innovative and reliable development solutions by leveraging our in-depth professional knowledge, adopting cutting-edge technologies, and enforcing strict quality control standards.

Professional Knowledge

Cutting-Edge Technologies

Quality Control

If you are looking to develop innovative drugs for prostate cancer, our expert team can provide comprehensive support. We are able to provide our clients with the expertise and technology to help take therapy programs from concept to practice. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.

Reference

  1. Malik, J. A., et al. Drug Repurposing: A New Hope in Drug Discovery for Prostate Cancer. ACS omega. 2022, 8(1): 56–73.
notification For research use only.

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