In recent years, with in-depth research on prostate cancer, there have been great advances in treatments for prostate cancer. Alfa Cytology focuses on development of multiple targeted therapies in prostate cancer, and aims to provide customers with comprehensive one-stop multiple therapeutic target modulator development services.
Prostate cancer affects millions of men worldwide. In recent years, there have been significant advances in the understanding of genomic landscapes and biological functions, and the therapy of prostate cancer has improved.
Fig. 1 Overview of therapeutic targeting strategies for the treatment of PCa. (He Y., et al. 2022)
A variety of novel agents, including next-generation androgen receptor (AR) signaling inhibitors, bone-targeting agents, and PARP inhibitors have been developed for the therapy of prostate cancer. Drugs targeting other signaling pathways, including CDK4/6, AKT, WNT, and epigenetic markers, have been entering clinical trials.
There has been a significant shift in prostate cancer therapy, with a focus on developing drugs that target specific molecular pathways and biomarkers.
Table 1 Theranostic agents approved for PCa in the 21st century. (He Y., et al. 2022)
Brand name | Pharmacotherapeutic group | EMA approval date | FDA approval date |
Zometa | Bone-targeting therapy | Mar 2001 | Feb 2002 |
Firmagon | Endocrine therapy | Feb 2009 | Dec 2008 |
Provenge | Immunotherapy | Sept 2013 | Apr 2010 |
Jevtana | Antineoplastic agents | Mar 2011 | Jun 2010 |
Prolia/Xgeva | Bone-targeting therapy | July 2011 | Nov 2010 |
Zytiga | Endocrine therapy | Sept 2011 | Apr 2011 |
Xtandi | Endocrine therapy | Jun 2013 | Aug 2012 |
Xofigo | Therapeutic radiopharmaceuticals | Nov 2013 | May 2013 |
Axumin | Diagnostic radiopharmaceuticals | May 2017 | May 2016 |
Keytruda | Immunotherapy | / | May 2017 |
Tookad | Antineoplastic agents | Sept 2017 | / |
Nubeqa | Endocrine therapy | Mar 2020 | Jul 2019 |
Rubraca | Antineoplastic agents | / | May 2020 |
Lynparza | Antineoplastic agents | Nov 2020 | May 2020 |
Orgovyx | Endocrine therapy | Mar 2022 | Dec 2020 |
Pylarify | Diagnostic radiopharmaceuticals | / | May 2021 |
Jemperli | Immunotherapy | / | Aug 2021 |
Pluvicto | Therapeutic radiopharmaceuticals | / | Mar 2022 |
Locametz | Diagnostic radiopharmaceuticals | / | Mar 2022 |
There have been many advances in prostate cancer therapies in the past few years as a result of in-depth research. As an innovative company, Alfa Cytology develops multiple targeted therapies for prostate cancer, and can one-stop multiple therapeutic target modulator development services.
One-stop small molecule inhibitor development provides target ID and validation, hit ID and optimization, lead optimization, candidate selection, and candidate profiling.
Therapeutic antibody development involves target identification, target validation, antibody generation, lead antibody selection and preclinical research services.
Specific cells are modified, cultured and expanded, and finally the resulting cells are characterized to develop cellular drugs for the therapy of prostate cancer.
Our expertise encompasses neoantigen vaccine, multiepitope vaccine, mRNA vaccine and so on, each of which provides comprehensive end-to-end services.
Utilizing various types of oncolytic virus-engineered systems, our services encompass everything from virus engineering and cell biology to animal testing.
Alfa Cytology provides customized RDC drug development, including antibody radionuclide conjugate (ARC), peptide radionuclide conjugate (PRC), and small molecule radionuclide conjugate (SMRC).
Alfa Cytology offers a full range of services for multiple therapeutic target modulator in prostate cancer, including but not limited to the following.
PARP | CDK4/6 | p53 | PSMA | ICI |
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WNT | VEGF | TGFβ | NRTKs | MEK/ERK |
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Our company is committed to providing customized one-stop services to accelerate your project development. With professional knowledge, we are committed to providing you with reliable experimental solutions, efficiently providing you with round-the-clock development services to ensure that your development is of low cost and confidentiality.
Qualified Experiment
Timely Delivery
Cost-Effective Services
Highly Confidential
With our expertise and resources, we aim to contribute to the development of multiple therapeutic target modulator, thereby improving patient outcomes and contributing to the fight against prostate cancer. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.
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