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Other Therapeutic Target Modulator Development

In recent years, with in-depth research on prostate cancer, there have been great advances in treatments for prostate cancer. Alfa Cytology focuses on development of multiple targeted therapies in prostate cancer, and aims to provide customers with comprehensive one-stop multiple therapeutic target modulator development services.

Introduction to Other Therapeutic Target Modulator

Prostate cancer affects millions of men worldwide. In recent years, there have been significant advances in the understanding of genomic landscapes and biological functions, and the therapy of prostate cancer has improved.

Fig. 1 Overview of therapeutic targeting strategies for the treatment of PCa. (He Y., et al. 2022)Fig. 1 Overview of therapeutic targeting strategies for the treatment of PCa. (He Y., et al. 2022)

A variety of novel agents, including next-generation androgen receptor (AR) signaling inhibitors, bone-targeting agents, and PARP inhibitors have been developed for the therapy of prostate cancer. Drugs targeting other signaling pathways, including CDK4/6, AKT, WNT, and epigenetic markers, have been entering clinical trials.

Other Therapeutic Target Modulator Development for Prostate Cancer

There has been a significant shift in prostate cancer therapy, with a focus on developing drugs that target specific molecular pathways and biomarkers.

Table 1 Theranostic agents approved for PCa in the 21st century. (He Y., et al. 2022)

Brand name Pharmacotherapeutic group EMA approval date FDA approval date
Zometa Bone-targeting therapy Mar 2001 Feb 2002
Firmagon Endocrine therapy Feb 2009 Dec 2008
Provenge Immunotherapy Sept 2013 Apr 2010
Jevtana Antineoplastic agents Mar 2011 Jun 2010
Prolia/Xgeva Bone-targeting therapy July 2011 Nov 2010
Zytiga Endocrine therapy Sept 2011 Apr 2011
Xtandi Endocrine therapy Jun 2013 Aug 2012
Xofigo Therapeutic radiopharmaceuticals Nov 2013 May 2013
Axumin Diagnostic radiopharmaceuticals May 2017 May 2016
Keytruda Immunotherapy / May 2017
Tookad Antineoplastic agents Sept 2017 /
Nubeqa Endocrine therapy Mar 2020 Jul 2019
Rubraca Antineoplastic agents / May 2020
Lynparza Antineoplastic agents Nov 2020 May 2020
Orgovyx Endocrine therapy Mar 2022 Dec 2020
Pylarify Diagnostic radiopharmaceuticals / May 2021
Jemperli Immunotherapy / Aug 2021
Pluvicto Therapeutic radiopharmaceuticals / Mar 2022
Locametz Diagnostic radiopharmaceuticals / Mar 2022

Our Services

There have been many advances in prostate cancer therapies in the past few years as a result of in-depth research. As an innovative company, Alfa Cytology develops multiple targeted therapies for prostate cancer, and can one-stop multiple therapeutic target modulator development services.

Small molecule inhibitors

One-stop small molecule inhibitor development provides target ID and validation, hit ID and optimization, lead optimization, candidate selection, and candidate profiling.

Therapeutic Antibody

Therapeutic antibody development involves target identification, target validation, antibody generation, lead antibody selection and preclinical research services.

Cell Therapy

Specific cells are modified, cultured and expanded, and finally the resulting cells are characterized to develop cellular drugs for the therapy of prostate cancer.

Therapeutic Vaccine

Our expertise encompasses neoantigen vaccine, multiepitope vaccine, mRNA vaccine and so on, each of which provides comprehensive end-to-end services.

Oncolytic Viral Therapy

Utilizing various types of oncolytic virus-engineered systems, our services encompass everything from virus engineering and cell biology to animal testing.

RDC Therapy

Alfa Cytology provides customized RDC drug development, including antibody radionuclide conjugate (ARC), peptide radionuclide conjugate (PRC), and small molecule radionuclide conjugate (SMRC).

Development Types for Other Therapeutic Target Modulator Development

Alfa Cytology offers a full range of services for multiple therapeutic target modulator in prostate cancer, including but not limited to the following.

PARP CDK4/6 p53 PSMA ICI
  • Small molecule inhibitors
  • Small molecule inhibitors
  • Small molecule inhibitors
  • Therapeutic Antibody
  • Cell Therapy
  • Therapeutic Vaccine
  • Small molecule inhibitors
  • Monoclonal Antibody
  • PSMA-ADC
  • CAR-T Cell Therapy
  • Small molecule inhibitors
  • Monoclonal Antibody
WNT VEGF TGFβ NRTKs MEK/ERK
  • Small molecule inhibitors
  • Therapeutic Antibody
  • Small molecule inhibitors
  • Monoclonal Antibody
  • Oncolytic Viral Therapy
  • Small molecule inhibitors
  • Therapeutic Antibody
  • Small molecule inhibitors
  • Monoclonal Antibody
  • Small molecule inhibitors

Our Advantages

Our company is committed to providing customized one-stop services to accelerate your project development. With professional knowledge, we are committed to providing you with reliable experimental solutions, efficiently providing you with round-the-clock development services to ensure that your development is of low cost and confidentiality.

Qualified Experiment

Timely Delivery

Cost-Effective Services

Highly Confidential

With our expertise and resources, we aim to contribute to the development of multiple therapeutic target modulator, thereby improving patient outcomes and contributing to the fight against prostate cancer. If you are interested in our services, please don't hesitate to contact us for further information and pricing details.

Reference

  1. He Y., et al. Targeting signaling pathways in prostate cancer: mechanisms and clinical trials. Signal Transduct Target Ther. 2022, 7(1):198.
notification For research use only.

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