Comprehensive Preclinical Solutions Provider
Specially Designed for Leukemia Small Molecule Drug Development

It’s time to find a partner who advances your research.

Make Speed, Simplicity and Reliability your competitive advantage.

Alfa Cytology's integrated CRO solutions streamline your R&D process.

Leukemia are blood cancers of which there are several variants and corresponding features. It’s this variation that leads scientists to design special treatments for each one.

Comprehensive Leukemia Specialist

WE SOLVE YOUR CHALLENGES IN

NO MATTER WHERE YOU ARE IN
LEUKEMIA SMALL MOLECULE DRUG DEVELOPMENT

We Offer Customized Solutions for You

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Hit-to-Lead

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Lead Optimization

  • Chemical modification
  • Structure-activity relationship (SAR) directed optimization
  • Structure-based drug design
  • Iterative optimization
  • Computer-aided drug design
  • Molecular modeling
  • Predictive ADME/toxicity modeling
  • Virtual screening
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Mechanism of Action (MoA) Studies

  • Compound binding determination
  • Target protein functional analysis
  • Biophysical and biochemical analysis
  • Multiomics analysis
  • Computational analysis
  • Gene expression profiling
  • Drug resistance mechanism research
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Explore our drug development capabilities

Meet the complex demands of innovative drug development
for different promising targets


IMMUNE CHECKPOINT INHIBITORs have been engineered as therapies for immune checkpoint failure in leukemia cells and immune escape in the cancers.

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HYPOMETHYLATING AGENT DEVELOPMENT may provide innovative solutions for breakthrough approaches to leukemia research and therapy, since gene mutations that involve methylation are implicated in the condition.

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HEDGEHOG PATHWAY INHIBITORs suppress the overexpression of the Hedgehog (Hh) signaling pathway in leukemia, which is associated with the maintenance of leukemia stem cells, thereby affect the outcome of patients.

  • Smoothened (SMO) inhibitor development
  • GLI inhibitor development
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TARGETED DRUG DEVELOPMENT AGAINST HTLV-1 to find innovative treatments and improve prognosis for adult T-cell leukemia (ATL).

  • Against transactivator from the X-gene region (Tax)
  • Against HTLV-1 basic leucine zipper factor (HBZ)
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LEUKEMIA CELL SURFACE ANTIGENs play an important role in diagnosing and classifying the disease and can also serve as binding sites for the development of targeted therapeutic approaches.

  • Small molecule inhibitors targeting cell surface antigens
  • Other targeted therapy development
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Streamlined Small Molecule Drug R&D Process

Initial Consultation & Needs Assessment

Beginning with an initial consultation, we get a deep insight into your specific project requirements to make sure our services are completely compatible with your goals and compliances.

Tailored Proposal Development

Following discussion, we build you a one-to-one proposal for scope, approach, timeline and costing, specifically suited to your drug development needs.

Preclinical Drug Development & Quality Assurance

Preclinical drug development and validation is carried out by our team using advanced tools and techniques. All the way through, we have strict quality assurance processes so that the output can be reliable and accurate.

Findings Delivery & Reporting

Once the project is complete, we deliver a full report including all of the results, expert insights and takeaways. We validate that the report is as promised to you and meets all regulatory expectations before finalizing.

Ongoing Support Commitment

We do not stop after you have finished your project, we will support you with the next analysis or changes as your project evolves.

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