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Learn MoreBiomarkers in brain tumors are essential in guiding cancer care, aiding in early detection, therapeutic decisions and ongoing prognosis monitoring. Alfa Cytology excels at providing advanced biomarker analysis services, empowering our clients to identify novel tumor biomarkers and evaluate their potential for early disease diagnosis and drug prognosis of brain tumors.
With the continuous advancement of omics technology, multiple biomarkers such as Isocitrate dehydrogenase (IDH) and O6-methylguanine-DNA methyltransferase have been identified and extensively studied for brain tumors. Moreover, due to the challenges in obtaining brain tumor tissue samples, noninvasive liquid biopsies are now emerging as a vital approach to brain tumor biomarker discovery, which offers a promising tool for detecting and monitoring brain tumors through easily accessible bodily fluids. Common analytes of liquid biopsies for tumors include evaluation of circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and cell-free DNA (cfDNA).
Fig.1 Biomarkers of glioma. (Hao M., et al., 2023)
The analysis of brain tumor biomarkers plays a pivotal role in the early detection of brain tumors, which is closely related to improved outcomes and survival rates for brain tumor patients. Further, biomarker analysis facilitates the development of personalized therapeutics tailored to the specific tumor phenotype and serves as a powerful tool to monitor drug response and tumor recurrence.
At Alfa Cytology, we are committed to the identification and evaluation of brain tumor biomarkers and aim to advance diagnostic development of brain tumors. The services we provide include but are not limited to the following analyses.
Genetic and Epigenomic Analysis
Specializing in advanced omics services that encompass genomics, epigenomics, and transcriptomic analyses, Alfa Cytology offers tailored solutions for the identification of biomarkers associated with brain tumors.
Protein Expression Analysis
Alfa Cytology offers cutting-edge proteomics and metabolomics analysis services powered by our advanced mass spectrometry technology, aiming to provide novel insights into brain tumor biology.
Immunophenotype Analysis
Well-established flow cytometry immunophenotyping assays are offered to characterize and quantify specific cell populations based on their surface markers to monitor cellular dynamics in response to therapeutic interventions.
Comprehensive liquid biopsy analyses are provided for the identification and evaluation of circulating tumor DNA (ctDNA), cell-free DNA (cfDNA), circulating tumor cells (CTCs) and other pertinent biomarkers in blood or cerebrospinal fluid, which help researchers better understand the initiation, progression and metastasis of brain tumors.
Alfa Cytology provides a diverse range of highly effective brain tumor biomarker analyses to meet the requirements of our clients. With our advanced and well-established methods, we hope to pave the way for more personalized and effective therapeutic strategies. If you have any inquiries or would like to learn more about our biomarker analysis services for brain tumors, please feel free to contact us.
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