Pineal tumors are rare neoplasms arising from the pineal gland, a small endocrine organ located near the center of the brain. At Alfa Cytology, we are committed to pioneering new therapeutic approaches for pineal tumors treatment for our clients.
Introduction to Pineal Tumors
Pineal tumors represent less than 1% of all intracranial tumors in adults, yet they present significant diagnostic and therapeutic challenges due to their diverse histological subtypes and complex biological behavior. The most common types include pineal parenchymal tumors, particularly pineocytomas and pineoblastomas, and germ cell tumors, which predominantly.
Pineal Parenchymal Tumors
- Germinoma
- Embryonal carcinoma
- Yolk sac tumor
- Choriocarcinoma
- Teratoma, mature and immature
- Teratoma with somatictype malignancy
- Mixed germ cell tumor
- Pineocytoma
- Pineal parenchymal tumor of intermediate differentiation
- Pineoblastoma
- Papillary tumor of the pineal region
- Desmoplastic myxoid tumor of the pineal region, SMARCB1-mutant
- Diffuse gliomas
- Circumscribed astrocytic gliomas
- Glioneuronal and neuronal tumors
- Embryonal tumors
- Meningiomas
- Mesenchymal nonmeningothelial tumors
- Lymphomas
Therapeutic Development for Pineal Tumors
The therapeutic landscape for pineal tumors is evolving, with a focus on multimodal approaches that include surgery, radiotherapy, and chemotherapy. The choice of treatment is influenced by the tumor's histological subtype, grade, and individual patient characteristics.
|
NCT |
Target |
Therapeutics |
Phase |
| NCT01182883 |
Type I Insulin-Like Growth Factor Receptor (IGF-1R) Inhibitor |
IMC-A12 |
|
| NCT03173950 |
PD-1 Inhibitor |
Nivolumab |
|
| NCT02596828 |
mTOR Inhibitor with Multi-Kinase Inhibitor |
Temozolomide and Irinotecan |
|
Our Services
At Alfa Cytology, we are dedicated to advancing research and therapeutic development for pineal tumors. Our comprehensive preclinical research services are designed to address the unique challenges presented by these rare neoplasms.
Contact Us
For researchers, healthcare providers, and pharmaceutical companies interested in collaborating on projects related to pineal tumors, Alfa Cytology is here to provide the expertise and resources necessary for groundbreaking research. To learn more about our services or to discuss potential collaborations, please feel free to
contact us.
Reference
- Lombardi, G.; et al. (2022). Diagnosis and Treatment of Pineal Region Tumors in Adults: A EURACAN Overview[J]. Cancers. 14, 3646.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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