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Learn MoreThe development of brain tumor therapeutics goes through several processes, drug discovery, preclinical studies, and clinical studies. Preclinical studies refer to studies in which the subjects are non-human. The purpose of preclinical studies is to provide preliminary testing of drug safety issues. Sometimes, preclinical studies can also provide some relevant information about the efficacy of a drug and lay the foundation for human trials of the drug.
Alfa Cytology can provide you with preclinical services around brain tumor research to help you perform maximum tolerated dose and maximum non-toxic dose experiments to determine the starting dose that can be used in humans. You can use our services to get recommendations for dose, route, and timing of administration for Phase I studies, as well as to observe whether the side effects of the drug can be reversed.
In vitro assays are evolving to be simpler, faster, non-invasive, and multi-informative. We offer a variety of in vitro assays for brain tumors using multiple methods at multiple levels and stages of disease development. We help you to conduct early screening of brain tumor patients, guide treatment protocols, treatment monitoring, and recurrence monitoring.
Animal models are the cornerstone of non-clinical evaluation work and are necessary before entering clinical trials. We are actively establishing a variety of animal models for brain tumor research to help you study the pathogenesis of brain tumors and treatment options.
Cell lines are more homogeneous and standardized than primary cultured cells and have an important role in brain tumor drug screening and toxicology studies. We can provide our clients with a variety of cell line development services and work on the development of brain tumor stem cells. This complete system can meet your multiple needs for brain tumor drug screening and disease research.
We offer genetically modified neural stem cell lines, which are genetically engineered to genetically modify neural stem cells to stably express specific exogenous genes, such as fluorescent proteins, neurotransmitter probes, calcium probes, and light-sensitive proteins.
We provide our customers with mice with a single genetic background and use rAAV vector to carry the target genome into the mice so that we can achieve the modeling of the corresponding disease animals and provide you with the relevant viral products. We can achieve large-scale production with high yield and stability.
Alfa Cytology helps you capture potential opportunities and make early and informed decisions to maximize the likelihood of successful clinical studies with our brain tumor in vitro assay services, model-building services, and cell line development services. Don't hesitate to contact us to help you with your brain tumor mechanistic insights and targeted drug discovery.